This report presents the findings of a national survey of work-related wellbeing in higher education. The sample comprised 6439 respondents working in academic and academic-related roles in UK universities and colleges. The Health and Safety Executive framework for measuring work-related stress was used and findings compared with data obtained in previous waves of the research. Other factors, such as perceptions of stress, illegitimate tasks and change fatigue and job satisfaction were examined. Mental and physical health, absenteeism and presenteeism and work-life balance were also assessed. The implications for UK higher education are discussed.